2003.09~2006.06  M.S., Nanchang University, Jiangxi Province, P.R. China 

2015.09~2019.01  Ph.D.,  Nanchang University, Jiangxi Province, P.R. China 

2006.07~present  Teaching Assistant,  Lecturer,  Associate Professor,  Professor,  College of Food Science and Technology, Nanchang University, Jiangxi Province, P.R. China 

Research interest

Dr. Zhou’s lab mainly focuses on: 

1. Bioactivity and Mechanisms of Medicinal-Food Homologous Functional Molecules, and Product Development;

2. Bio-Manufacturing of Functional Nutraceuticals (Synthetic Biology).

Selected publications

1. Wang Z, Chen K, Zhang K, He K, Zhang D, Guo X, Huang T, Hu J, Zhou X, * Nie S *., Agrocybe cylindracea fucoglucogalactan induced lysosome-mediated apoptosis of colorectal cancer cell through H3K27ac-regulated cathepsin D. Carbohydrate Polymers 2023, 319, 121208. （IF=11.2）

2. Huang T.; Zhang K.; Wang J.; He K, Zhou X, * Nie S*., Quercetin Alleviates Acrylamide-Induced Liver Injury by Inhibiting Autophagy-Dependent Ferroptosis. J Agric Food Chem 2023, 71(19):7427-7439. （IF=6.1）

3. Zhang D.; Zhou X.; * Zhou W.; Cui SW.; Nie S*., Intestinal organoids: A thriving and powerful tool for investigating dietary nutrients-intestinal homeostasis axis. Food Res Int 2023, 172. （IF=8.1）

4. Zhang, D.; Zhou, X.; * Zhang, K.; Yu, Y.; Cui, SW.; Nie, S*., Glucomannan from Aloe vera gel maintains intestinal barrier integrity via mitigating anoikis mediated by Nrf2-mitochondria axis. Int J Biol Macromol 2023, 235, 123803. （IF=8.2）

5. Liu, L.; Zhang, D.; Song, X.; Guo, M.; Wang, Z.; Geng, F.; Zhou, X.; * Nie, S., * Compound hydrogels derived from gelatin and gellan gum regulates the release of anthocyanins in simulated digestion. Food hydrocolloids 2022, 127, 107487.（IF=10.7）

6.Zhang, K.; Zhang, D.; Wang, J.; Wang, Y.; Hu, J.; Zhou, Y.; Zhou, X.; * Nie, S.; Xie, M., * Aloe gel glucomannan induced colon cancer cell death via mitochondrial damage-driven PINK1/Parkin mitophagy pathway. Carbohydr Polym 2022, 295, 119841.（IF=11.2）

7. Zhou, Y.; Zhou, X.; * Huang, X.; Hong, T.; Zhang, K.; Qi, W.; Guo, M.; Nie, S., * Lysosome-Mediated Cytotoxic Autophagy Contributes to Tea Polysaccharide-Induced Colon Cancer Cell Death via mTOR-TFEB Signaling. J Agric Food Chem 2021, 69 (2), 686-697.（IF=6.1）

8. Zhang, D.; Zhou, X.; * Liu, L.; Guo, M.; Huang, T.; Zhou, W.; Geng, F.; Cui, S. W.; Nie, S.,* Glucomannan from Aloe vera Gel Promotes Intestinal Stem Cell-Mediated Epithelial Regeneration via the Wnt/beta-Catenin Pathway. J Agric Food Chem 2021, 69 (36), 10581-10591.（IF=6.1）

9.  Zhou, X.; Zhang, D.; Qi, W.; Hong, T.; Xiong, T.; Wu, T.; Geng, F.; Xie, M.; Nie, S., Exopolysaccharides from Lactobacillus plantarum NCU116 Facilitate Intestinal Homeostasis by Modulating Intestinal Epithelial Regeneration and Microbiota. J Agric Food Chem 2021, 69 (28), 7863-7873.（IF=6.1）

10. Zhang, K.; Zhou, X.; * Wang, J.; Zhou, Y.; Qi, W.; Chen, H.; Nie, S.; Xie, M., * Dendrobium officinale polysaccharide triggers mitochondrial disorder to induce colon cancer cell death via ROS-AMPK-autophagy pathway. Carbohydr Polym 2021, 264, 118018.（IF=11.2）