Scientific Research Achievements

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1.      Zong Z#, Ren J#, Yang B, Zhang L, Zhou F: Emerging roles of lysine lactyltransferases and lactylation. Nature Cell Biology 2025, 27(4):563-574.

2.      Ren J, Liu S, Zhang L: Inhibitor of differentiation 3 confers the robust anti-tumor activity of Kupffer cells. MedComm 2024, 5(9):e708.

3.      Ren J#, Wang S#, Zong Z, Pan T, Liu S, Mao W, Huang H, Yan X, Yang B, He X*, Zhou F*, Zhang L*. TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence. Nature Communications 2024, 15(1):244.

4.      Ren J#, Yu P#, Liu S#, Li R, Niu X, Chen Y, Zhang Z, Zhou F, Zhang L: Deubiquitylating Enzymes in Cancer and Immunity. Advanced Science 2023:e2303807.

5.      Ren J#, Zhang Z#, Zong Z, Zhang L, Zhou F: Emerging Implications of Phase Separation in Cancer. Advanced Science 2022:e2202855.

6.      Zong Z#, Wei Y#, Ren J#, Zhang L, Zhou F: The intersection of COVID-19 and cancer: signaling pathways and treatment implications. Molecular Cancer 2021, 20:76.

7.      Ren J, Wang Y, Ware T, Iaria J, Ten Dijke P, Zhu HJ: Reactivation of BMP signaling by suboptimal concentrations of MEK inhibitor and FK506 reduces organ-specific breast cancer metastasis. Cancer Letters 2020, 493:41-54.

8.      Ren J, Smid M, Iaria J, Salvatori DCF, van Dam H, Zhu HJ, Martens JWM, Ten Dijke P: Cancer-associated fibroblast-derived Gremlin 1 promotes breast cancer progression. Breast Cancer Research 2019, 21:109.

9.      Sow HS#, Ren J#, Camps M, Ossendorp F, Ten Dijke P: Combined Inhibition of TGF-β Signaling and the PD-L1 Immune Checkpoint Is Differentially Effective in Tumor Models. Cells 2019, 8.

10.    Ren J, Liu S, Cui C, Ten Dijke P: Invasive Behavior of Human Breast Cancer Cells in Embryonic Zebrafish. Journal of Visualized Experiments 2017.

11.    Ren J, Ten Dijke P: Bone Morphogenetic Proteins in the Initiation and Progression of Breast Cancer. Bone Morphogenetic Proteins: Systems Biology Regulators 2017, 409–433.

12.    Ren J, Yu C, Wu S, Peng F, Jiang Q, Zhang X, Zhong G, Shi H, Chen X, Su X, Zhu W, Wei Yuquan: Cationic liposome mediated delivery of FUS1 and hIL-12 coexpression plasmid demonstrates enhanced activity against human lung cancer. Current Cancer Drug Targets 2014, 14:167-180.

13.    Huang QD#, Ren J#, Chen H, Ou WJ, Zhang J, Fu Y, Zhu W, Yu XQ: Cyclen-Based Cationic Lipids Containing Carbamate Linkages as Efficient Gene Delivery Vectors with Low Toxicity. ChemPlusChem 2012, 77:584-591.

14.    Huang QD#, Ren J#, Ou WJ, Fu Y, Cai MQ, Zhang J, Zhu W, Yu XQ: Cationic lipids containing cyclen and ammonium moieties as gene delivery vectors. Chemical Biology & Drug Design 2012, 79:879-887.

15.    Liu S, Ren J, Ten Dijke P: Targeting TGFβ signal transduction for cancer therapy. Signal Transduction and Targeted Therapy 2021, 6:8.

16.    Barone M, Müller M, Chiha S, Ren J, Albat D, Soicke A, Dohmen S, Klein M, Bruns J, van Dinther M, et al: Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells. PNAS 2020, 117:29684-29690.

17.    Sundqvist A, Morikawa M, Ren J, Vasilaki E, Kawasaki N, Kobayashi M, Koinuma D, Aburatani H, Miyazono K, Heldin CH, et al: JUNB governs a feed-forward network of TGFβ signaling that aggravates breast cancer invasion. Nucleic Acids Research 2018, 46:1180-1195.