个人信息

姓名:徐小文

论文成果

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以第一或通讯作者发表的论文情况:

[1] Yu T, Li M, Zhang H, Hu J, Li M, Zhang Q, Liu X, Fu Z, Hu C*, Xu X*. Zebrafish ZDHHC11 palmitoylates STING to potentiate antiviral immune response. Cell Communication and Signaling, 2026.

[2] Zhao K, Zhang Y, Yin Z, Tan L, Juario M, Zhang H, Liu Y, Xu P, Zhang Q, Zhao G, Wang S, Mao H, Xu X*Hu C*. GCRV-II major outer capsid protein VP4 promotes cell apoptosis by VDAC2-mediated calcium pathway facilitation. International Journal of Biological Macromolecules, 2025, 285, 138273. 共同通讯作者

[3] Guo R, Wu Y, Yu T, Guo C, Yin Z, Zhao G, Li M, Mao H, Hu C, Xu X*Tetrachlorantraniliprole induces neurodevelopmental toxicity through oxidative stress-mediated apoptosis and dysregulation of Wnt signaling pathway. Aquatic Toxicology, 2025, 279, 107229. 通讯作者

[4] Zhang Y, Zhao K, Liu Y, Xu J, Zhang H, Yin Z, Xu P, Jiang Z, Wang S, Mao H, Xu X*, Hu C*. An oral probiotic vaccine loaded by Lactobacillus casei effectively increases defense against GCRV infection in grass carp. Vaccine, 2025, 45, 126660. 共同通讯作者

[5] Yu T, Li M, Li M, Wang S, Feng Z, Zhang H, Liu J, Mao H, Li D, Hu C*, Xu X*. Zebrafish (Danio rerio) TDP43 negatively regulates PKZ-IRF3–mediated IFN I response. Journal of Immunology, 2025, 214(4): 726-746.共同通讯作者

[6] Yu T, Li M, Li M, Zhang Q, Zhang H, Jiang Z, Wang S, Mao H, Li D, Fan L, Hu C*, Xu X*. Zebrafish TDP43 positively regulates p65-mediated apoptotic pathway. International Journal of Biological Macromolecules, 2025, 27, 142599. 共同通讯作者

[7] Zhang Q, Yu T, Wang Z, Li M, Xu J, Liu X, Qian C, Yin Z, He G, Hu M, Zhang B, Liu J, Fu Z, Wang S*, Xu X*, Hu C. RBCK1 enhances antiviral response through promoting K63-linked polyubiquitination of IRF7 in Carassius auratus var. PengzeFish and Shellfish Immunology, 2025, 165, 110532.共同通讯作者

[8] Zhang H, Liu X, Yin Z, Zhao K, Zhang Q, Yu T, Liu J, Zhang B, Hu M, Jiang Z, Li M, Wang S, Hu C*, Xu X*. ISGylation of zebrafish STING at lysines 221 and 276 activates innate immunityFish and Shellfish Immunology, 2025, 166, 110640. 共同通讯作者

[9] Guo C, Yu T, Guo R, Li M, Huang X, Wu Y, Tang J, Zhang Z, Wang S, Hu C*, Xu X*. Gpx4a-mediated ferroptosis underlines prothioconazole-induced ocular defects in early-life zebrafish. Water Biology and Security, 2025. 共同通讯作者

[10] Yin Z, Zhang H, Zhao K, Liu Y, Guo R, Xu P, Zhao G, Hu M, Hu C, Xu X*. Zebrafish FKBP5 facilitates apoptosis and SVCV propagation by suppressing NF-κB signaling pathway. Fish and Shellfish Immunology, 2024, 155, 110021. 通讯作者

[11] Li MM, Tao CB, Li MF, Wu CX, Yu TT, Feng ZQ, Zhang Q, Jiang ZY, Mao HL, Wang SH, Xu XW*, Hu CY*. A molecular mechanism underlies grass carp (Ctenopharyngodon idella) TARBP2 regulating PKR-mediated cell apoptosis. Fish and Shellfish Immunology, 2024, 154, 109906. 共同通讯作者

[12] Li M, Hu J, Zhou J, Wu C, Li D, Mao H, Kong L, Hu C*, Xu X*. Grass carp (Ctenopharyngodon idella) deacetylase SIRT1 targets p53 to suppress apoptosis in a KAT8 dependent or independent manner. Fish and Shellfish Immunology, 2023, 109264. 共同通讯作者

[13] Han X#, Xu X#, Yu T, Li M, Liu Y, Lai J, Mao H, Hu C, Wang S*. Dilfubenzuron Induces Cardiotoxicity in Zebraflsh Embryos. International Journal of Molecular Sciences, 2022, 23, 11932. 共同第一作者

[14] Xiong Y, Wang C*, Dong M, Li M, Hu C, Xu X*. Chlorphoxim induces neurotoxicity in zebrafish embryo through activation of oxidative stress. Environmental Toxicology, 2022, 10: 1-13. 共同通讯作者

[15] Yu T, Zeng Q, Mao H*, Liu Y, Zhang H, Wang S, Hu C, Xu X*. Grass carp (Ctenopharyngodon idella) NLK2 inhibits IFN I response through blocking MAVS-IRF3 axis. Fish and Shellfish Immunology, 2022, 131: 206-217. 共同通讯作者

[16] Wang S, Han X, Yu T, Liu Y, Zhang H, Mao H, Hu C, Xu X*. Isoprocarb causes neurotoxicity of zebrafish embryos through oxidative stress-induced apoptosis. Ecotoxicology and Environmental Safety, 2022, 242, 113870. 通讯作者

[17] Li M, Hu J, Mao H, Li D, Jiang Z, Sun Z, Yu T, Hu C*, Xu X*. Grass Carp (Ctenopharyngodon idella) KAT8 inhibits IFN 1 response through acetylating IRF3/IRF7. Frontiers in Immunology, 2022, 12, 808159. 共同通讯作者

[18] Xu X, Li M, Deng Z, Li D, Lu S, Deng H, Lv Y, Liu Y, Du H, Hu C*. Grass carp Mre11A activates IFN 1 response by targeting STING to defend against GCRV infection. Developmental and Comparative Immunology, 2021,116, 103909. 第一作者

[19] Xu X, Li M, Deng Z, Hu J, Jiang Z, Liu Y, Chang K, Hu C*. Grass Carp (Ctenopharyngodon idellus) NIMA-Related Kinase Blocks dsRNA-Induced IFN Response by Targeting IRF3. Frontiers in Immunology. 2021, 11, 597775. 第一作者

[20] Li M, Yu T, Lai J, Han X, Hu J, Deng Z, Li D, Ye Z, Wang S, Hu C*Xu X*. Ethoprophos induces cardiac toxicity in zebrafish embryos. Ecotoxicology and Environmental Safety. 2021, 228, 113029. 共同通讯作者

[21] Xu X, Li M, Deng Z, Jiang Z, Li D, Wang S, Hu C*. cGASa and cGASb from grass carp (Ctenopharyngodon idellus) play opposite roles in mediating type I interferon response. Developmental and Comparative Immunology, 2021, 125, 104233. 第一作者

[22] Lu S, Peng X, Lin G, Xu K, Wang S, Qiu W, Du H, Chang K, Lv Y, Liu Y, Deng H, Hu C, Xu X*Grass carp (Ctenopharyngodon idellus) SHP2 suppresses IFN I expression via decreasing the phosphorylation of GSK3β in a non-contact manner. Fish and Shellfish Immunology. 2021, 116: 150-160. 通讯作者

[23] Xu X, Li M, Wu C, Li D, Jiang Z, Liu C, Cheng B, Mao H, Hu C. The Fish-Specific Protein Kinase (PKZ) Initiates Innate Immune Responses via IRF3- and ISGF3-Like Mediated Pathways. Frontiers in Immunology. 2019, 10, 582. 第一作者

[24] Xu X, Li M, Li D, Jiang Z, Liu C, Shi X, Wu C, Chen X, Lin G, Hu C* Identification of the SAMHD1 gene in grass carp and its roles in inducing appotosis and inhibiting GCRV proliferation. Fish & Shellfish Immunology, 2019, 88: 606-618. 第一作者

[25] Xu XLi MWu ZWang HWang LHuang KLiu XHou QLin GHu CEndoplasmic reticulum transmembrane proteins ZDHHC1 and STING both act as direct adaptors for IRF3 activation in teleost. Journal of Immunology, 2017, 199(10):3623-3633. 第一作者

[26] Xu XLai QGu MLiu DHou QLiu XMi YSun ZWang HLin GHu C* Fish IRF3 up-regulates the transcriptional level of IRF1, IRF2, IRF3 and IRF7 in CIK cellsFish & Shellfish Immunology2015,47:978-985. 第一作者

[27] 胡美玲,于婷婷,卢君焱,花佳丽,龚慧莹,杨珊珊,胡成钰,徐小文*斑马鱼TDP43负调控Ⅰ型干扰素的表达南昌大学学报(理科版),202448(2): 173-182. 通讯作者

[28] 胡成钰,张岩松,徐小文*鱼用疫苗研究进展南昌大学学报(理科版),202448(1): 77-86. 通讯作者

[29] 胡霁欢,胡美玲,史晓,周鹏程,常凯乐,向阳,徐小文*草鱼(Ctenopharyngodon idella)长链非编码RNA ISG152-L2激活IRF3ISG152的表达,南昌大学学报,202347(3):272-282. 通讯作者