1. Chen X, Li Q, Zhang W, Xu Y, Nie X, Wang X, Chen C, Xie J*, Nie S*. Akkermansia muciniphila-derived extracellular vesicles alleviate colitis-related cognitive impairment via tryptophan metabolic reprogramming of the gut-brain axis. Gut Microbes. 2026 Jan 18(1): 2611546. (IF=11.0; Q1)

2. Nie X, Li Q, Fatima H, Wang Y, Meng F, Xie J*, Nie S*. Advances in mammalian, plant, and bacterial-derived extracellular vesicles for cancer therapy. Chemical Engineering Journal. 2025 Nov 1;532: 168637 (IF=13.2; Q1)

3. Li Q, Chen X, Wang Y, Meng F, Xie J*, Nie S*. Engineered bacterial extracellular vesicles: developments, challenges, and opportunities. Engineering. 2025 Jul 22 (IF=11.6; Q1)

4. Nie X, Li Q, He Y, Xu Y, Qiao S, Wang X, Meng F, Xie J*, Nie S*. Engineered bacterial extracellular vesicles for gastrointestinal diseases. Journal of Controlled Release. 2025 Sep 10;385: 113972 (IF=11.5; Q1)

5.  Xie J^#, Burgelman M^#, Dujardin P, et al. Gut microbiota modulates CNS barrier function in murine model for multiple sclerosis. Fluids and Barriers of the CNS. 2025 Nov 22, 114 (IF= 6.2; Q1)

6. Xie J^#, Van Hoecke L^#, Van Wonterghem E, Van Imschoot G, Andries V, Lars Vereecke L, Vandenbroucke R*. The gut-brain axis in Alzheimer's disease is shaped by commensal gut microbiota derived extracellular vesicles. Gut Microbes. 2025 Dec;17(1):2501193 (IF=11.0; Q1)

7. Nie X, Li Q, Ji H, Zhang S, Wang Y, Xie J*, Nie S*. Bifidobacterium longum-derived extracellular vesicles ameliorate ulcerative colitis by modulating T cell responses in gut microbiota-(in)dependent manners. npj Biofilms and Microbiomes. 2025 Feb; 11(1): 27. (IF=7.8; Q1; highly cited paper)

8. Chen X, Li Q, Xie J*, Nie S*. Immunomodulatory effects of probiotic-derived extracellular vesicles: opportunities and challenges. Journal of Agricultural and Food Chemistry. 2024 Sep 4;72(35):19259-19273. (IF=6.1; Q1)

9. Nie X, Li Q, Chen C, Onyango S, Xie J*, Nie S*. Bacterial extracellular vesicles: Vital contributors to physiology from bacteria to host. Microbiological Research. 2024 Apr 25:284:127733 (IF=6.7; Q1)

10. Xie J, Van Hoecke L, Van Wonterghem E, et al. The gut-brain axis in Alzheimer’s disease is shaped by commensal gut microbiota derived extracellular vesicles. Gut Microbes. 2025 May; 17(1). (IF=12.2; Q1)

11. Xie J, Li Q, Nie S, et al. Bacterial extracellular vesicles: An emerging postbiotic. Trends in Food Science & Technology. 2023 Dec;31(12):1206-1224 (IF=15.3; Q1)

12. Xie J, Cools L, Van Imschoot G, et al. Helicobactor pylori-derived outer membrane vesicles contribute to Alzheimer’s disease pathogenesis via C3-C3aR signaling. Journal of Extracellular Vesicles. 2023 Feb;12(2):e12306 (IF=16.0; Q1; highly cited paper)

13. Xie J, Haesebrouck F, Van Hoecke L, et al. Bacterial extracellular vesicles: An emerging avenue to tackle diseases. Trends in Microbiology. 2023 Jun (IF=15.9; Q1; highly cited paper)

14. Xie J, Bruggeman A, De Nolf C, et al. Gut microbiota regulates blood-cerebrospinal fluid barrier function and Aβ pathology. The EMBO Journal. 2023 Jul: e111515 (IF=11.4; Q1)

15. Xie J, Li Q, Haesebrouck F, et al. The tremendous biomedical potential of bacterial extracellular vesicles. Trends in Biotechnology. 2022 Oct;40(10):1173-1194. (IF=17.3; Q1; highly cited paper)

16. Xie J, Van Hoecke L, Vandenbroucke RE*. The impact of systemic inflammation on Alzheimer's disease pathology. Frontiers in Immunology. 2022 Jan 6;12:796867. (IF=7.3; Q1; highly cited paper)

17. Xie J, Gorlé N, Vandendriessche C, Van Imschoot G, Van Wonterghem E, Van Cauwenberghe C, Parthoens E, Van Hamme E, Lippens S, Van Hoecke L, Vandenbroucke RE*. Low-grade peripheral inflammation affects brain pathology in the App^NL-G-F mouse model of Alzheimer's disease. Acta Neuropathologica Communications. 2021 Oct 7;9(1):163. (IF= 7.1; Q1)

18. Xie J, Fan S, Nie S*, Yu Q, Xiong T, Gong D, Xie M. Lactobacillus plantarum NCU116 attenuates cyclophosphamide-induced intestinal mucosal injury, metabolism and intestinal microbiota disorders in mice. Food & Function. 2016 Mar;7(3):1584-1592. (IF= 6.1; Q1)

19. Xie J, Nie S*, Yu Q, Yin J, Xiong T, Gong D, Xie M. Lactobacillus plantarum NCU116 attenuates cyclophosphamide-induced immunosuppression and regulates Th17/Treg cell immune responses in mice. Journal of Agricultural and Food Chemistry. 2016 Feb 17;64(6):1291-1297. (IBA1=6.1; Q1)

20. Xie J, Yu Q, Nie S*, Fan S, Xiong T, Xie M. Effects of Lactobacillus plantarum NCU116 on intestine mucosal immunity in immunosuppressed mice. Journal of Agricultural and Food Chemistry. 2015 Dec 30;63(51):10914-10920. (IF= 6.1; Q1)