个人信息

姓名:雷江涛

国籍:中国

性别:

毕业院校:复旦大学

职称:助理研究员

学位:博士

职称类别:中级

导师类型:硕士生导师

电子邮件:jiangtaolei@ncu.edu.cn

所在单位:空间科学与技术研究院

办公地址:空间科学与技术研究院313

个人信息

科研成果

20. Wencan Liu, Xinwei Zhou, Shucai Zou, Zhengguang Hu, Yun Shen, Mengqiang Cai, Dongdong Lin, Jia Zhou, Xiaohua Deng, Tianjing Guo*, Jiangtao Lei*. High-sensitivity polarizationindependent terahertz Taichi-like micro-ring sensors based on toroidal dipole resonance for concentration detection of A protein, Nanophotonics2023, 12(6): 1177-1187 (2023)(IF:7.923)

19. Jiangtao Lei*, Xuanyao Li, Mengqiang Cai, Tianjing Guo, Dongdong Lin, Xiaohua Deng and Yin Li*. Insights into Allosteric Mechanisms of the Lung-Enriched p53 Mutants V157F and R158L. International Journal of Molecular Sciences, 23(17):10100 (2022). (IF: 6.208)

18. Ling Xu, Jianwei Xu, Wencan Liu, Dongdong Lin, Jiangtao Lei*, Binbin Zhou, Yun Shen, Xiaohua Deng . Terahertz metal-graphene hybrid metamaterial for monitoring aggregation of Aβ16-22 peptides, Sensors and Actuators B: Chemical, 367(15), 132016 (2022). (IF: 9.221)

17. Yin Li, Yiwen Sun, Qiqi Li, Jiangtao Lei, Bo Yang, Yun Shen, Yingxiang Cai, Xiaohua Deng. Temperature-Dependent Terahertz Spectra of Isonicotinamide in the Form I Studied Using the Quasi-Harmonic Approximation. ChemPhysChem 23, e202100849 (2022). (IF: 3.502)

16. Le Li, Xuewei Dong, Yiming Tang, Zenghui Lao, Xuhua Li, Jiangtao Lei, Guanghong Wei*.Deciphering the mechanisms of HPV E6 mutations in the destabilization of E6/E6AP/p53 complex.Biophysical Journal, 121(9):1704-1714. (2022). (IF: 3.699)

15. Jiangtao Lei* Mengqiang Cai, Dongdong Lin, Yun Shen, Xiaohua Deng*. Molecular dynamics study on the inhibition mechanisms of ReACp53 peptide for p53-R175H mutant aggregation.Physical chemistry chemical physics, 23(40): 23032-23041 (2021). (IF: 3.906)

14. Dongdong Lin, Jiangtao Lei (共1), Shujie Li, Xingfei Zhou, Gaunghong Wei, and Xinju Yang* Investigation of the Dissociation Mechanism of Single-Walled Carbon Nanotube on Mature Amyloid‑β Fibrils at Single Nanotube Level. The Journal of Physical Chemistry B.124:3459-3468(2020). (IF: 2.857)

13. Le Li, Xuhua Li, Yiming Tang, Zenghui Lao, Jiangtao Lei and Guanghong Wei* Common cancer mutations R175H and R273H drive the p53 DNA-binding domain towards aggregation-prone conformations. Physical chemistry chemical physics. 22:9925 22(17):9225-9232 (2020). (IF: 3.906)

12. Vasantha Basavalingappa, Tom Guterman, Yiming Tang, Sivan Nir, Jiangtao Lei, Priyadarshi Chakraborty, Lee Schnaider, Meital Reches, Guanghong Wei*, Ehud Gazit* Expanding the Functional Scope of the Fmoc-Diphenylalanine Hydrogelator by Introducing a Rigidifying and Chemically Active Urea Backbone Modification. Advanced science 6(12):1900218, (2019). (IF: 13.116)

11. Xuhua Li, Jiangtao Lei, Ruxi Qi, Luogang Xie, Guanghong Wei*Mechanistic insight into E22Q-mutation-induced antiparallel-to-parallel β-sheet transition of Aβ 16-22 fibrils: an all-atom simulation study. Physical chemistry chemical physics. 21(28):15686-15694. (2019) (IF: 3.906)

10. Yibo Jin, Yunxiang Sun,Yujie Chen, Jiangtao Lei, Guanghong Wei*. Molecular dynamics simulations reveal the mechanism of graphene oxide nanosheet inhibition of Aβ1-42 peptide aggregation. Physical chemistry chemical physics. 21(21):10981-10991 (2019). (IF: 3.906)

9. Cuiqin Bai, Dongdong Lin, Yuxiang Mo, Jiangtao Lei, Yunxiang Sun, Luogang Xie, Xinju Yang and Guanghong Wei*. Influence of fullerenol on hIAPP aggregation: amyloid inhibition and mechanistic aspects. Physical chemistry chemical physics. 20(7):4022-4031(2019). (IF: 3.906)

8. Jiangtao Lei, Ruxi Qi, Yegen Tang, Wenning Wang, Guanghong Wei*, Ruth Nussinov, and Buyong Ma*. Conformational stability and dynamics of the cancer-associated isoform ∆133p53β are modulated by p53 peptides and p53-specific DNA. The FASEB Journal, 33(3):4225-4235 (2019). (IF: 5.595)

7. Noam Brown, Jiangtao Lei, Chendi Zhan, Linda J. W. Shimon, Lihi Adler-Abramovich, Guanghong Wei* and Ehud Gazit*. Structural Polymorphism in a Self-Assembled Tri-Aromatic Peptide System. ACS nano. 12(4): 3253-3262 (2018). (IF: 13.709)

6. Yuxiang Mo, Sayanti Brahmachari, Jiangtao Lei, Sharon Gilead, Yiming Tang, Ehud Gazit* and Guanghong Wei*. The inhibitory effect of hydroxylated carbon nanotubes on the aggregation of human islet amyloid polypeptide revealed by a combined computational and experimental study.  ACS Chemical Neuroscience,9(11): 2741-2752 (2018). (IF: 4.211)    

5. Yibo Jin, Yunxiang Sun, Jiangtao Lei, Guanghong Wei*. Dihydrochalcone molecules destabilize Alzheimer’s amyloid-β protofibrils by disrupting N-terminal β-sheets and D23-K28 salt bridges through binding to the protofibril cavity. Physical chemistry chemical physics. 20(25):17208-17217 (2018). (IF: 3.906) 

4. Yujie Chen, Zihan Chen, Yunxiang Sun, Jiangtao Lei, Guanghong Wei*. Mechanistic Insights into the Inhibition and Size effects of Graphene Oxide Nanosheets on the Aggregation of an Amyloid-β Peptide Fragment. Nanoscale, 10(19): 8989-8997 (2018). (IF: 7.233)  

3. Jiangtao Lei, Ruxi Qi, Luogang Xie, Wenhui Xi, Guanghong Wei*. Inhibitory effect of hydrophobic fullerenes on the β-sheet-rich oligomers of a hydrophilic GNNQQNY peptide revealed by atomistic simulations. RSC Advances, 7(23): 13947-13956 (2017). (IF: 2.936)   

2. Jiangtao Lei, Ruxi Qi, Guanghong Wei*, Ruth Nussinov and Buyong Ma*. Self-aggregation and coaggregation of p53 core fragment with its aggregation Gatekeeper variant. Physical Chemistry Chemical Physics, 18(11): 8098-8107 (2016). (IF: 3.906) 

1. Yuxiang Mo, Jiangtao Lei, Yunxiang Sun, Qingwen Zhang and Guanghong Wei*. Conformational Ensemble of hIAPP Dimer: Insight into the Molecular Mechanism by which a Green Tea Extract inhibits hIAPP Aggregation. Scientific Reports, 6: 33076 (2016). (IF: 4.122)