个人信息

姓名:叶海峰

国籍:中国

性别:

毕业院校:慕尼黑大学

职称:副研究员

学位:博士

职称类别:副高级

岗位类别:教学科研岗位

岗位级别:副高七级

电子邮件:haifeng.ye@ncu.edu.cn

所在单位:生物医学创新研究院

办公地址:医学院科创大楼303室

个人信息


研究兴趣与领域:皮肤创伤修复与再生

教研室:生理教研室

教育经历

[1] 201809-202304 慕尼黑大学 博士研究生

[2] 201509-201807 南昌大学 硕士研究生

[3] 201009-201507 南昌大学 大学本科

工作履历

[1] 202210-202312 德国亥姆霍兹研究中心-再生生物医学研究所 德国亥姆霍兹研究中心-再生生物医学研究所

科研成果

主持课题

1.国家自然科学基金委员会,青年科学基金项目(C类),82402919,SFRP2通过Wnt/β-catenin信号通路调控筋膜动员在皮肤伤口愈合中的作用及机制研究,2025-01-01至2027-12-31,30万元,主持

2.国家自然科学基金委员会,面上项目,82572888,巨噬细胞胞外陷阱Mets调控成纤维细胞时空分化介导筋膜动员在皮肤伤口愈合中的作用及机制研究,2026-01-01至2029-12-31,48万元,主持

3.江西省科技厅,自然科学基金-青年基金项目,S20254132,IGFBP5通过IGF1信号通路调控筋膜动员在皮肤伤口愈合中的作用及机制研究,2025-06-01至2027-06-01,10万元,主持

4.江西省委组织部,2024年引培生项目,10万元,主持


第一作者发表文章*(影响因子以当年为准)

1:Correa-Gallegos D#, Ye H#, Dasgupta B#, Sardogan A, Kadri S, Kandi R, Dai R, Lin Y, Kopplin R, Shenai Disha S, Wannemacher J, Ichijo R, Jiang D, Strunz M, Ansari M, Angelidis I, Schiller H, Voltz T, Hans-Günther M, Rinkevich Y*. Spatiotemporal differentiation of CD201-expressing fascia progenitors choreographs injury repair, Nature. 2023, https://doi.org/10.1038/s41586-023-06725-x 共同第一作者. 影响因子 69.504

2:Xu J, Zhang H, Ye H. Research progress on the role of fascia in skin wound healing.Burns Trauma. 2025 Apr 16;13:tkaf002. 最后通讯. 影响因子 6.3

3: Yu C, Li Y, Liu Z, Ye W, Wei L, Xu W, Yan L, Ye H. RTP4 Suppresses Colorectal Cancer Progression via MHC-I-Mediated CD8+ T Cell Infiltration and Enhances Immunotherapy Response. J Cell Mol Med. 2025 Oct;29(20):e70915. 最后通讯. 影响因子 4.2

4:Huang Y, Ye H. Female germline stem cells: recent advances, opportunities, and challenges to overcome. Cell Regen. 2025 Aug 12;14(1):34. 最后通讯. 影响因子 4.7

5:Ye H, Rinkevich Y. Fascia Layer-A Novel Target for the Application of Biomaterials in Skin Wound Healing. Int J Mol Sci. 2023 Feb 2;24(3):2936 . 影响因子 6.208

6: Ye H, Zheng T, Li W, Li X, Fu X, Huang Y, Hu C, Li J, Huang J, Liu Z, Zheng L, Zheng Y. Ovarian Stem Cell Nests in Reproduction and Ovarian Aging. Cell Physiol Biochem. 2017;43(5):1917-1925. 影响因子 5.500

7:Ye H, Li X, Zheng T, Hu C, Pan Z, Huang J, Li J, Li W, Zheng Y. The Hippo Signaling Pathway Regulates Ovarian Function via the Proliferation of Ovarian Germline Stem Cells. Cell Physiol Biochem. 2017;41(3):1051-1062. 影响因子 5.500

8:Ye H, Li X, Zheng T, Liang X, Li J, Huang J, Pan Z, Zheng Y. The effect of the immune system on ovarian function and features of ovarian germline stem cells. Springerplus. 2016 Jul 7;5(1):990. 影响因子 1.249

 

共同作者发表文章

1: Correa-Gallegos D#, Jiang D#, Christ S, Ramesh P, Ye H, Wannemacher J, Kalgudde Gopal S, Yu Q, Aichler M, Walch A, Mirastschijski U, Volz T, Rinkevich Y. Patch repair of deep wounds by mobilized fascia. Nature. 2019 Dec;576(7786):287-292. 影响因子42.778

2: Fischer A#, Wannemacher J#, Christ S#, Koopmans T, Kadri S, Zhao J, Gouda M, Ye H, Mück-Häusl M, Krenn PW, Machens HG, Fässler R, Neumann PA, Hauck SM, Rinkevich Y. Neutrophils direct preexisting matrix to initiate repair in damaged tissues. Nat Immunol. 2022 Apr;23(4):518-531. 影响因子31.25 

3:Jiang D#, Christ S#, Correa-Gallegos D#, Ramesh P#, Kalgudde Gopal S, Wannemacher J, Mayr CH, Lupperger V, Yu Q, Ye H, Mück-Häusl M, Rajendran V, Wan L, Liu J, Mirastschijski U, Volz T, Marr C, Schiller HB, Rinkevich Y. Injury triggers fascia fibroblast collective cell migration to drive scar formation through N-cadherin. Nat Commun. 2020 Nov 6;11(1):5653. 影响因子 14.919

4:Wan L#, Jiang D#, Correa-Gallegos D, Ramesh P, Zhao J, Ye H, Zhu S, Wannemacher J, Volz T, Rinkevich Y. Connexin43 gap junction drives fascia mobilization and repair of deep skin wounds. Matrix Biol. 2021 Mar; 97:58-71. 影响因子 10.447

5: Li X, Ye H, Su T, Hu C, Huang Y, Fu X, Zhong Z, Du X, Zheng Y. Immunity and reproduction protective effects of Chitosan Oligosaccharides in Cyclophosphamide/Busulfan-induced premature ovarian failure model mice. Front Immunol. 2023 May 9;14:1185921. 影响因子8.786

6: Rajendran V, Ramesh P, Dai R, Kalgudde Gopal S, Ye H, Machens HG, Adler H, Jiang D, Rinkevich Y. Therapeutic Silencing of p120 in Fascia Fibroblasts Ameliorates Tissue Repair. J Invest Dermatol. 2022 Nov 26:S0022-202X(22)02821-4. 影响因子 7.590

7: Zheng K#, Hong W#, Ye H, Zhou Z, Ling S, Li Y, Dai Y, Zhong Z, Yang Z, Zheng Y. Chito-oligosaccharides and macrophages have synergistic effects on improving ovarian stem cells function by regulating inflammatory factors. J Ovarian Res. 2023 Apr 14;16(1):76. 影响因子5.506

8: Xu J, Zheng T, Hong W, Ye H, Hu C, Zheng Y. Mechanism for the Decision of Ovarian Surface Epithelial Stem Cells to Undergo Neo-Oogenesis or Ovarian Tumorigenesis. Cell Physiol Biochem. 2018;50(1):214-232. 影响因子5.500

9: Huang Y, Ye H, Zhu F, Hu C, Zheng Y. The role of Chito-oligosaccharide in regulating ovarian germ stem cells function and restoring ovarian function in chemotherapy mice. Reprod Biol Endocrinol. 2021 Jan 25;19(1):14. 影响因子 4.67

10: Jiang D, de Vries JC, Muschhammer J, Schatz S, Ye H, Hein T, Fidan M, Romanov VS, Rinkevich Y, Scharffetter-Kochanek K. Local and transient inhibition of p21 expression ameliorates age-related delayed wound healing. Wound Repair Regen. 2020 Jan;28(1):49-60. 影响因子3.617

11:Huang Y, Hu C, Ye H, Luo R, Fu X, Li X, Huang J, Chen W, Zheng Y. Inflamm-Aging: A New Mechanism Affecting Premature Ovarian Insufficiency. J Immunol Res. 2019 Jan 2;2019:8069898. 影响因子 3.000

12:Liu Y, Xu J, Zhu F, Ye H, Hu C, Huang J, Zheng Y. Research advances in the regulation of the putative ovarian germline stem cell niche on female germline stem cells. Syst Biol Reprod Med. 2019 Apr;65(2):121-128. 影响因子1.77

13:Ramesh P, Ye H, Dasgupta B, Machens HG, Rinkevich Y. Visualizing Scar Development Using SCAD Assay - An Ex-situ Skin Scarring Assay. J Vis Exp. 2022 Apr 28;(182). 影响因子 1.424