刘进，博士/教授，南昌大学藻类创新工程研究中心主任

微藻是古老的微生物，绝大多数能够进行光合作用，固定CO2并释放氧气，是地球碳-氧循环的重要参与者和至关重要的初级生产力。微藻具有光能利用效率高、生长快、环境适应性强、不与粮争地等多方面的优势，被誉为理想的光驱细胞工厂。除了能将固定的CO2转化成油脂和碳水化合物等储能物质，微藻还能合成一系列的高值产物，在食品、健康、能源和环境等领域有重要的应用前景。

藻类创新工程研究中心立足“双碳”战略目标和绿色生物经济发展规划等国家需求，致力于通过交叉学科前沿技术开展特色藻类资源的基础及工程应用研究。中心主要研究方向包括：1）微藻光合固碳、抗逆与代谢调控；2）微藻功能基因组学与合成生物学；3）藻菌互作与资源化利用。

刘进（中山大学本科和硕士，香港大学博士），国家海外高层次人才（青年），曾先后就职于亚利桑那州立大学、马里兰大学、北京大学，长期致力于藻类代谢与合成生物研究，在植物学领域(Molecular Plant, New Phytologist, Plant Physiology, Plant Journal)和工程技术领域(Nature Communications, Metabolic Engineering, Biotechnology for Biofuels, Bioresource Technology)等TOP期刊发表论文60余篇，主持国家重点研发计划课题、国家自然科学基金面上和国际合作等多个科研项目（总经费超过2000万）。曾入选“科学中国人”2018年度人物、全球前 2%顶尖科学家“年度影响力”榜单（2020-2022）等。

ResearchGate: https://www.researchgate.net/profile/Jin-Liu

Google schorlar: https://scholar.google.com/citations?user=BKjCZPkAAAAJ&hl=en

学术任职和服务

国际期刊Algal Research，副主编

国际期刊Advanced Biotechnology，副主编

国际期刊Frontiers in Marine Science, 栏目副主编

国际期刊Frontiers in Plant Science, 编委

国际期刊Agriculture, 编委

国际期刊The Innovation Life，学术编辑

国际期刊Green Carbon，青年编委

国际应用藻类学会，执行委员

中国海洋湖沼学会藻类学分会，常务委员

中国生物工程学会农业生物工程专委会，委员

中国植物生理与植物分子生物学学会能源植物专委会，委员

评审国家重点研发计划项目、高等学校自然科学奖、国家自然科学基金等百余项

国家重点研发计划项目启动会和中期评审专家

作为组织委员会执行主席组织了第一届微藻碳中和高峰论坛

作为组织委员会和学术委员会成员参与组织第10届亚太藻类生物技术国际会议(10th Asia-Pacific Conference on Algal Biotechnology)，任分会主席

国际期刊Algal Research、Advanced Biotechnology、Biotechnology for Biofuels and Bioproducts、Frontiers in Marine Science、Frontiers in Microbiology、Marine Drugs等专刊编辑

Nature Communications等知名期刊审稿人

• 200608-201011 香港大学 博士研究生
• 200309-200506 中山大学 硕士研究生
• 199909-200306 中山大学 大学本科

• [1] 2010年8月-2011年4月 香港大学生物科学学院，研究助理
• [2] 2011年5月-2012年10月 美国亚利桑那州立大学，博士后
• [3] 2012年11月-2015年7月 美国马里兰大学环境科学中心，助理研究员
• [4] 2015年8月-2023年7月 北京大学工学院，研究员
• [5] 2023年8月-至今 南昌大学资源与环境学院，教授

• [1]国家自然科学基金面上项目：代谢重塑光驱真核微藻合成高值产物的机理研究，2025－2028，50万，主持
• [2]国家自然科学基金面上项目：佐夫色绿藻虾青素生物合成和酯化的途径解析和调控机制研究，2021－2024，58万，主持
• [3]国家重点研发计划课题：单细胞真核微藻基因组编辑改造与表达调控的机理，2019－2024，655万，主持
• [4]江西省“双千计划”创新领军人才短期项目：微藻资源化利用，2019-2022，50万元，主持
• [5]国家自然科学基金面上项目：微藻甘油三酯代谢的表观遗传调控机制研究，2018－2021，65万，主持

1.        Jiang M, Zheng J, Tang Y, Liu H, Yao Y, Zhou J, Lin W, Ma Y*, Liu J*, Zhou J* (2025) Retrievable hydrogel networks with confined microalgae for efficient antibiotic degradation and enhanced stress tolerance. Nature Communications 16: 3160.

2.        Zheng J, Wei H, Shi J, Yu L, Luo M, Li Y, Li-Beisson Y, Liu J* (2025) A histone demethylase is involved in regulating the transcription factor PSR1 for carbon storage in Chlamydomonas. The Plant Journal 122: e70230.

3.        Zheng J, Shi Y, Yu L, Sun H, Zhou W, Liu J* (2025) Modulation of an omega-3 fatty acid desaturase for eicosapentaenoic acid biosynthesis in the alga Nannochloropsis oceanica. Algal Research 85: 103877.

4.        Liu, M, Zheng J, Yu L, Shao S, Zhou W, Liu J* (2024) Engineering the marine alga Nannochloropsis oceanica for concurrent production of canthaxanthin and eicosapentaenoic acid. Bioresource Technology, 413: 131525

5.        Liu M, Yu L, Zheng J, Shao S, Pan Y, Hu H, Shen L, Wang W, Zhou W, Liu J* (2024) Turning the industrially relevant marine alga Nannochloropsis red: One move for multifaceted benefits. New Phytologist, 244: 1467-1481

6.        Xu P, Shao S, Qian J, Li J, Xu R, Liu J*, Zhou W* (2024). Scale-up of microalgal systems for decarbonization and bioproducts: Challenges and opportunities. Bioresource Technology :130528.

7.        Ye Y, Liu M, Yu L, Sun H*, Liu J* (2024). Nannochloropsis as an emerging algal chassis for light-driven synthesis of lipids and high-value products. Marine Drugs 22:54.

8.        Sun H, Gong Q, Fan Y, Wang Y, Wang J, Zhu C, Mou H, Yang S, Liu J* (2024) Unlocking 3D printing technology for microalgal production and application. Advanced Biotechnology 2: 36.

9.        Sun H, Liu J* (2023) Research progress and prospects in lipid metabolic engineering of eukaryotic microalgae. Synthetic Biology Journal 4: 1140-1160

10.    Ye Y, Ding W, Huang J, Liu J* (2023) Characterization of a Chromochloris zofingiensis mutant with enhanced canthaxanthin accumulation. Algal Research 75: 103260

11.    Qian J, Xu C, Song H, Zhou W, Toda T, Li H, Takayama Y, Sekine M, Koga S, Li J*, Liu J*. Enhancing algal growth and nutrient recovery from anaerobic digestion piggery effluent by an integrated pretreatment strategy of ammonia stripping and flocculation. Frontiers in Bioengineering and Biotechnology. 2023; 11: 1219103

12.    Liu M, Ding W, Pan Y, Hu H, Liu J*. Zeaxanthin epoxidase is involved in carotenoid biosynthesis and light-dependent growth of the marine alga Nannochloropsis oceanica. Biotechnology for Biofuels and Bioproducts. 2023; 16: 74.

13.    Shi M, Yu L, Shi J, Liu J*. A conserved MYB transcription factor is involved in regulating lipid metabolic pathways for oil biosynthesis in green algae. New Phytologist. 2022; 235: 576-594.

14.    Bai F, Yu L, Shi J, Li-Beisson Y, Liu J*. Long-chain acyl-CoA synthetases activate fatty acids for lipid synthesis, remodeling and energy production in Chlamydomonas. New Phytologist. 2022; 233: 823-837.

15.    Liu J*, Liu M, Shi Y, Pan Y, Hu H. Metabolic engineering of the oleaginous alga Nannochloropsis for enriching eicosapentaenoic acid in triacylglycerol by combined pulling and pushing strategies. Metabolic Engineering. 2022; 69: 163-174.

16.    Ding W, Liu J*. Rutin Stimulates the green alga Chromochloris zofingiensis for improved biomass and astaxanthin production. Journal of Agricultural and Food Chemistry. 2022; 70: 13626–13636.

17.    Yang J#, Liu J#, Pan Y, Maréchal E, Amato A, Liu M, Gong Y, Li Y, Hu H*. PDAT regulates PE as transient carbon sink alternative to triacylglycerol in Nannochloropsis. Plant Physiology. 2022; 189: 1345–1362.

18.    Liu M, Ding W, Yu L, Shi Y, Liu J*. Functional characterization of carotenogenic genes provides implications into carotenoid biosynthesis and engineering in the marine alga Nannochloropsis oceanica. Algal Research, 2022; 67: 102853

19.    Wu T, Yu L, Zhang Y, Liu J*. Characterization of fatty acid desaturases reveals stress-induced synthesis of C18 unsaturated fatty acids enriched in triacylglycerol in the oleaginous alga Chromochloris zofingiensis. Biotechnology for Biofuels. 2021;14: 184

20.    Zhang Y, Ye Y, Bai F, Liu J*. The oleaginous astaxanthin-producing alga Chromochloris zofingiensis: potential from production to an emerging model for studying lipid metabolism and carotenogenesis. Biotechnology for Biofuels. 2021; 14: 119.

21.    Zhang Y#, Pan Y#, Ding W, Hu H, Liu J*. Lipid production is more than doubled by manipulating a diacylglycerol acyltransferase in algae. GCB Bioenergy. 2021; 13: 185–200

22.    Shi Y, Liu M, Pan Y, Hu H, Liu J*. Δ6 fatty acid elongase is involved in eicosapentaenoic acid biosynthesis via the ω6 pathway in the marine alga Nannochloropsis oceanica. Journal of Agricultural and Food Chemistry. 2021; 69: 9837−9848.

23.    Bai F, Zhang Y, Liu J*. A bZIP transcription factor is involved in regulating lipid and pigment metabolisms in the green alga Chlamydomonas reinhardtii. Algal Research. 2021; 59: 102450

24.    Zhang Y, Ye Y, Ding W, Mao X, Li Y, Gerken H, Liu J*. Astaxanthin is ketolated from zeaxanthin independent of fatty acid synthesis in Chromochloris zofingiensis. Plant Physiology. 2020; 183: 883-897.

25.    Wu T, Fu Y, Shi Y, Li Y, Kou Y, Mao X, Liu J*. Functional characterization of long-chain acyl-CoA synthetase gene family from the oleaginous alga Chromochloris zofingiensis. Journal of Agricultural and Food Chemistry. 2020; 68: 4473-4484.

26.    Shi Y, Liu M, Ding W, Liu J*. Novel insights into phosphorus deprivation-boosted lipid synthesis in the marine alga Nannochloropsis oceanica without compromising biomass production. Journal of Agricultural and Food Chemistry. 2020; 68: 11488–11502.

27.    Mao X#, Zhang Y#, Wang X#, Liu J*. Novel insights into salinity-induced lipogenesis and carotenogenesis in the oleaginous astaxanthin-producing alga Chromochloris zofingiensis: a multi-omics study. Biotechnology for Biofuels. 2020; 13: 73.

28.    Kou Y, Liu M, Sun P, Dong Z, Liu J*. High light boosts salinity stress-induced biosynthesis of astaxanthin and lipids in the green alga Chromochloris zofingiensis. Algal Research. 2020; 50: 101976

29.    Zhang Y, Shi M, Mao X, Kou Y, Liu J*. Time-resolved carotenoid profiling and transcriptomic analysis reveal mechanism of carotenogenesis for astaxanthin synthesis in the oleaginous green alga Chromochloris zofingiensis. Biotechnology for Biofuels. 2019; 12: 287.

30.    Wang X, Wei H, Mao X, Liu J*. Proteomics analysis of lipid droplets from the oleaginous alga Chromochloris zofingiensis reveals novel proteins for lipid metabolism. Genomics, Proteomics & Bioinformatics. 2019; 17: 260-272.

31.    Sun Z, Zhang Y, Sun L-p, Liu J*. Light elicits astaxanthin biosynthesis and accumulation in the fermented ultrahigh-density Chlorella zofingiensis. Journal of Agricultural and Food Chemistry. 2019; 67: 5579–5586.

32.    Sun Z, Wang X, Liu J*. Screening of Isochrysis strains for simultaneous production of docosahexaenoic acid and fucoxanthin. Algal Research. 2019; 41: 101545

33.    Shi M, Wei H, Chen Q, Wang X, Zhou W, Liu J*. Exploring an isolate of the oleaginous alga Micractinium inermum for lipid production: molecular characterization and physiochemical analysis under multiple growth conditions. Journal of Applied Phycology. 2019; 31: 1035-1046

34.    Mao X, Wu T, Kou Y, Shi Y, Zhang Y, Liu J*. Characterization of type I and type II diacylglycerol acyltransferases from the emerging model alga Chlorella zofingiensis reveals their functional complementarity and engineering potential. Biotechnology for Biofuels. 2019; 12: 28.

35.    Liu J*, Sun Z, Mao X, Gerken H, Wang X, Yang W. Multiomics analysis reveals distinct mechanism of oleaginousness in the emerging model alga Chromochloris zofingiensis. The Plant Journal. 2019; 98: 1060–1077.

36.    Sun Z, Wei H, Zhou Z-g, Ashokkumar M, Liu J*. Screening of Isochrysis strains and utilization of a two-stage outdoor cultivation strategy for algal biomass and lipid production. Applied Biochemistry and Biotechnology. 2018; 185: 1100–1117

37.    Ma X, Liu B, Yang B, Guo B, Liu J*, Chen F*. Physiochemical and gene expression analyses reveal differential responses of the marine oleaginous alga Nannochloropsis salina under different lipid-induction conditions. Journal of Applied Phycology. 2018; 30: 909–919

38.    Wei H, Shi Y, Ma X, Pan Y, Hu H, Li Y, Luo M, Gerken H, Liu J*. A type-I diacylglycerol acyltransferase modulates triacylglycerol biosynthesis and fatty acid composition in the oleaginous microalga, Nannochloropsis oceanica. Biotechnology for Biofuels. 2017; 10: 174.

39.    Zhou W*, Wang J, Chen P, Ji C, Kang Q, Lu B, Li K, Liu J*, Ruan R. Bio-mitigation of carbon dioxide using microalgal systems: Advances and perspectives. Renewable and Sustainable Energy Reviews. 2017; 76: 1163-1175.

40.    Yang B, Liu J*, Ma X, Guo B, Liu B, Wu T, Jiang Y, Chen F*. Genetic engineering of the Calvin cycle toward enhanced photosynthetic CO2 fixation in microalgae. Biotechnology for Biofuels. 2017; 10: 229.

41.    Xin Y#, Lu Y#, Lee Y-Y#, Wei L, Jia J, Wang Q, Wang D, Bai F, Hu H, Hu Q, Liu J*, Li Y*, Xu J*. Producing designer oils in industrial microalgae by rational modulation of co-evolving type-2 diacylglycerol acyltransferases. Molecular Plant. 2017; 10: 1523-1539.

42.    Sun Z, Chen Y, Mao X, Liu J*. Physiological and biochemical changes reveal differential patterns of docosahexaenoic acid partitioning in two marine algal strains of Isochrysis. Marine Drugs. 2017; 15: 357

43.    Ma X, Yao L, Yang B, Lee YK, Chen F*, Liu J*. RNAi-mediated silencing of a pyruvate dehydrogenase kinase enhances triacylglycerol biosynthesis in the oleaginous marine alga Nannochloropsis salina. Scientific Reports. 2017; 7: 11485

44.    Liu J*, Lee Y-Y, Mao X, Li Y*. A simple and reproducible non-radiolabeled in vitro assay for recombinant acyltransferases involved in triacylglycerol biosynthesis. Journal of Applied Phycology. 2017; 29: 323-333

45.    Zhang Z, Sun D, Mao X, Liu J*, Chen F*. The crosstalk between astaxanthin, fatty acids and reactive oxygen species in heterotrophic Chlorella zofingiensis. Algal Research. 2016; 19: 178-183

46.    Yang B, Liu J*, Jiang Y, Chen F*. Chlorella species as hosts for genetic engineering and expression of heterologous proteins: Progress, challenge and perspective. Biotechnology Journal. 2016; 11: 1244-1261.

47.    Ma X, Liu J*, Liu B, Chen T, Yang B, Chen F*. Physiological and biochemical changes reveal stress-associated photosynthetic carbon partitioning into triacylglycerol in the oleaginous marine alga Nannochloropsis oculata. Algal Research. 2016; 16: 28-35

48.    Ma X, Chen T, Yang B, Liu J*, Chen F*. Lipid Production from Nannochloropsis. Marine Drugs. 2016; 14: 61

49.    Liu J*, Mao X, Zhou W, Guarnieri MT. Simultaneous production of triacylglycerol and high-value carotenoids by the astaxanthin-producing oleaginous green microalga Chlorella zofingiensis. Bioresource Technology. 2016; 214: 319-327.

50.    Liu J, Han D, Yoon K, Hu Q*, Li Y*. Characterization of type 2 diacylglycerol acyltransferases in Chlamydomonas reinhardtii reveals their distinct substrate specificities and functions in triacylglycerol biosynthesis. The Plant Journal. 2016; 86: 3-19.

51.    Guo B, Liu B, Yang B, Sun P, Lu X, Liu J*, Chen F*. Screening of diatom strains and characterization of Cyclotella cryptica as a potential fucoxanthin producer. Marine Drugs. 2016; 14: 125

52.    Sun Z, Zhou Z-g, Gerken H, Chen F, Liu J*. Screening and characterization of oleaginous Chlorella strains and exploration of photoautotrophic Chlorella protothecoides for oil production. Bioresource Technology. 2015; 184: 53-62.

53.    Chen T#, Liu J#, Guo B, Ma X, Sun P, Liu B, Chen F*. Light attenuates lipid accumulation while enhancing cell proliferation and starch synthesis in the glucose-fed oleaginous microalga Chlorella zofingiensis. Scientific Reports. 2015; 5: 14936

54.    Liu J*, Sun Z, Gerken H, Liu Z, Jiang Y, Chen F*. Chlorella zofingiensis as an alternative microalgal producer of astaxanthin: biology and industrial potential. Marine Drugs. 2014; 12: 3487-3515

55.    Liu J*, Sun Z, Gerken H, Huang J, Jiang Y, Chen F*. Genetic engineering of the green alga Chlorella zofingiensis: a modified norflurazon-resistant phytoene desaturase gene as a dominant selectable marker. Applied Microbiology Biotechnology. 2014; 98: 5069-5079

56.    Liu J*, Gerken H, Li Y*. Single-tube colony PCR for DNA amplification and transformant screening of oleaginous microalgae. Journal of Applied Phycology. 2014; 26: 1719-1726

57.    Liu J*, Sun Z, Zhong Y, Gerken H, Huang J, Chen F*. Utilization of cane molasses towards cost-saving astaxanthin production by a Chlorella zofingiensis mutant. Journal of Applied Phycology. 2013; 25: 1447-1456

58.    Liu J, Sommerfeld M, Hu Q*. Screening and characterization of Isochrysis strains and optimization of culture conditions for docosahexaenoic acid production. Applied Microbiology and Biotechnology. 2013; 97: 4785-4798

59.    Liu J*, Gerken H, Huang J, Chen F*. Engineering of an endogenous phytoene desaturase gene as a dominant selectable marker for Chlamydomonas reinhardtii transformation and enhanced biosynthesis of carotenoids. Process Biochemistry. 2013; 48: 788-795

60.    Huangfu J#, Liu J#, Sun Z, Wang M, Jiang Y, Chen Z-Y, Chen F*. Antiaging effects of astaxanthin-rich alga Haematococcus pluvialis on fruit flies under oxidative stress. Journal of Agricultural and Food Chemistry. 2013; 61: 7800-7804.

61.    Huangfu J#, Liu J#, Peng C, Suen YL, Wang M, Jiang Y, Chen Z-Y, Chen F*. DHA-rich marine microalga Schizochytrium mangrovei possesses anti-ageing effects on Drosophila melanogaster. Journal of Functional Foods. 2013; 5: 888-896

62.    Liu J*, Sun Z, Zhong Y, Huang J, Hu Q, Chen F*. Stearoyl-acyl carrier protein desaturase gene from the oleaginous microalga Chlorella zofingiensis: Cloning, characterization and transcriptional analysis. Planta. 2012; 236: 1665-1676

63.    Liu J*, Huang J, Jiang Y, Chen F*. Molasses-based growth and production of oil and astaxanthin by Chlorella zofingiensis. Bioresource Technology. 2012; 107: 393-398.

64.    Liu J, Huang J*, Sun Z, Zhong Y, Jiang Y, Chen F*. Differential lipid and fatty acid profiles of photoautotrophic and heterotrophic Chlorella zofingiensis: Assessment of algal oils for biodiesel production. Bioresource Technology. 2011; 102: 106-110.

65.    Liu J, Zhong Y, Sun Z, Huang J*, Sandmann G, Chen F*. One amino acid substitution in phytoene desaturase makes Chlorella zofingiensis resistant to norflurazon and enhances the biosynthesis of astaxanthin. Planta. 2010; 232: 61-67

66.    Liu J, Huang J*, Fan KW, Jiang Y*, Zhong Y, Sun Z, Chen F. Production potential of Chlorella zofingienesis as a feedstock for biodiesel. Bioresource Technology. 2010; 101: 8658-8663.

67.    Huang J#, Liu J#, Li YT, Chen F*. Isolation and characterization of the phytoene desaturase gene as a potential selective marker for genetic engineering of the astaxanthin-producing green alga Chlorella zofingiensis (Chlorophyta). Journal of Phycology. 2008; 44: 684-690

68. Liu J#, Xia K-F#, Zhu J-C, Deng Y-G, Huang X-L, Hu B-L, Xu X, Xu Z-F*. Nightshade proteinase inhibitor IIb gene is constitutively expressed in glandular trichomes. Plant and Cell Physiology. 2006; 47: 1274-1284