学科方向：食品营养、功能食品

所属院系：食品科学与资源挖掘全国重点实验室

研究方向

      分子营养、食品蛋白质化学与营养、食源性活性小分子的健康效应及机制

个人经历

副研究员，硕导，食品科学与资源挖掘全国重点实验室固定成员，江西省青年人才，南昌大学赣江青年学者，中国营养学会蛋白质营养与健康分会常务委员，江西省营养学会理事。Journal of Agricultural and Food Chemistry、Food Chemistry等杂志审稿人。主持国家自然科学基金2项，江西省自然科学基金3项，江西省人才项目1项，企业横向课题5项；以第一/通讯作者在Food Research International、Journal of Agricultural and Food Chemistry、Molecular Nutrition & Food Research、Food & Function、The FASEB Journal等食品领域Top期刊发表SCI论文30余篇（其中2篇封面文章）；获省科学进步二等奖1项；公开国家发明专利3项。

讲授课程

食品营养学、实验动物学、生物统计学

学术成就

主持国家自然科学基金项目2项（含青年C类）、江西省自然科学基金（青年+面上）及省级人才项目多项。获江西省科技进步二等奖、首届江西省创新争先奖等荣誉。

承担课题

1. 国家自然科学基金委员会，青年科学基金项目（C类），32402081，红糖寡糖通过与铁螯合共同跨膜转运促铁吸收的作用及机制研究，2025-01-01至2027-12-31，30万元，在研，主持

2. 国家自然科学基金委员会，地区科学基金项目，82160614，基于FTO/m6A修饰调控IGF2BP1蛋白相分离探讨亚麻环肽抗血管内皮炎症的分子机制，2022-01-01至2025-12-31，35万元，在研，主持

3. 江西省科技厅，赣鄱俊才支持计划-主要学科学术和技术带头人培养项目--青年人才（学术类），20243BCE51070，基于热邻近共聚蛋白质组技术探讨牛、羊乳中乳铁蛋白在小肠中差异性吸收的机制，2024-01-01至2026-12-31，30万元，在研，主持

4. 江西省科技厅，自然科学面上基金项目，20252BAC240697，亚麻籽巯基环肽调控α-亚麻酸代谢协同抗血管炎症的作用及机制研究，2025-06-01至2027-06-30，10万元，在研，主持

5. 乳成分活性改造及其改善儿童生长发育和机制研究子课题“酪蛋白源矿物质活性肽制备及促矿物质吸收机制研究”，国家乳业技术创新中心，40万元，主持，2025.07-2028.06

6. 寡二糖有机矿物质吸收机制研究，南宁市泽威尔饲料有限责任公司，20万元，主持，2021.01-2022.07

7. 母乳及不同乳源（牛乳、羊乳）配方奶粉中蛋白质吸收的测定，海普诺凯营养品有限公司，10万元，主持，2022.04-2022.09

8. 母乳与牛羊乳中乳铁蛋白及寡肽的肠道差异性吸收机制研究，海普诺凯营养品有限公司，30万元，主持，2023.08-2025.01

论文专著

1. Hailing Song, Yun Ma, Qian Du, Zeyuan Deng, Yalun Zou, Yadong Miao, Jing Li and Liufeng Zheng*, Flaxseed cyclolinopeptide-mediated regulation of α-linolenic acid metabolism alleviates high-fat diet-induced vascular inflammation, Food & Function, 2026, 17(2): 957-972.

2. Hailing Song, Zeyuan Deng, Yalun Zou, Caidong Zhao, Jing Li and Liufeng Zheng*, Identification of antioxidant oligopeptides targeting Nrf2 from gastrointestinal digestion of casein glycomacropeptide, International Dairy Journal, 2025, 168: 106294.

3. Mengru Zhang, Zeyuan Deng, Hailing Song, Caidong Zhao, Yalun Zou, Yifei Li and Liufeng Zheng*, Whey protein and endogenous oligopeptide profiles: A comparative study of human and major domestic animal milk, Food Bioscience, 2025, 66: 106309.

4. Qian Du, Ruiyan Wang, Zeyuan Deng, Jianqun Zhou, Nan Li, Wenwen Li and Liufeng Zheng*, Structural characterization and calcium absorption‐promoting effect of sucrose‐calcium chelate in Caco‐2 monolayer cells and mice, Journal of Food Science, 2024, 89: 1773 - 1790.

5. Ting Gan, Qian Xing, Nan Li, Zeyuan Deng, Changxuan Pan, Xiaoru Liu and Liufeng Zheng*, Protective Effect of Vitexin Against IL‐17‐Induced Vascular Endothelial Inflammation Through Keap1/Nrf2‐Dependent Signaling Pathway, Molecular Nutrition & Food Research, 2024, 68(5): 2300331.

6. Wenwen Li, Zeyuan Deng, Shuang Xiao, Qian Du, Mengru Zhang, Hailing Song, Caidong Zhao and Liufeng Zheng*, Protective effect of vitexin against high fat-induced vascular endothelial inflammation through inhibiting trimethylamine N-oxide-mediated RNA m6A modification, Food & Function, 2024, 15(13): 6988-7002.

7. Nan Li, Ruiyan Wang, Zeyuan Deng, Jianqun Zhou, Wenwen Li, Qian Du and Liufeng Zheng*, Structural Characterization of Zinc–Sucrose Complex and Its Ability to Promote Zinc Absorption in Caco-2 Monolayer Cells and Mice, Journal of Agricultural and Food Chemistry, 2023, 71(31): 12094-12104.

8. Nan Li, Ruiyan Wang, Wenwen Li, Qian Du, Zeyuan deng, Yawei Fan and Liufeng Zheng*, Identification of OLA1 as a Novel Protein Target of Vitexin to Ameliorate Dextran Sulfate Sodium-Induced Colitis with Tissue Thermal Proteome Profiling, Journal of Agricultural and Food Chemistry, 2023, 71(43): 16057-16066.

9. Ting Xiao, Junpeng Zeng, Caidong Zhao, Yanmei Hou, Tong Wu, Zeyuan Deng and Liufeng Zheng*, Comparative Analysis of Protein Digestion Characteristics in Human, Cow, Goat, Sheep, Mare, and Camel Milk under Simulated Infant Condition, Journal of Agricultural and Food Chemistry, 2023, 71(41): 15035-15047.

10. Wenli Huang, Zeyuan Deng, Ling Lu, Yaoming Ouyang, Shuyuan Zhong, Ting Luo, Yawei Fan* and Liufeng Zheng*, Polysaccharides from soybean residue fermented by Neurospora crassa alleviate DSS-induced gut barrier damage and microbiota disturbance in mice, Food & Function, 2022, 13(10): 5739-5751.

11. Nan Li, Leyun Qiu, Hailing Song, Ting Xiao, Ting Luo, Zeyuan Deng and Liufeng Zheng*, Inhibition mechanism of oligopeptides from soft‐shelled turtle egg against α‐glucosidase and their gastrointestinal digestive properties, Journal of Food Biochemistry, 2022, 46(10): e14328.

12. Xiaoping Li#, Liufeng Zheng#, Bing Zhang, Ze-Yuan Deng and Ting Luo, The Structure Basis of Phytochemicals as Metabolic Signals for Combating Obesity, Frontiers in nutrition, 2022, 9: 913883.

13. Ting Xiao, Junpeng Zeng, Leyun Qiu, Ruiyan Wang, Nan Li, Zeyuan Deng* and Liufeng Zheng*, Combining in silico and in vitro approaches to identify endogenous hypoglycemic peptides from human milk, Food & Function, 2022, 13(5): 2899-2912.

14. Leyun Qiu, Zeyuan Deng, Caidong Zhao, Ting Xiao, Chen Weng, Jing Li and Liufeng Zheng*, Nutritional composition and proteomic analysis of soft-shelled turtle (Pelodiscus sinensis) egg and identification of oligopeptides with alpha-glucosidase inhibitory activity, Food Research International, 2021, 145: 110414.

15. Chen Weng, Ze-Yuan Deng, Niu Zhang, Qian Zou, Ya-Wei Fan, Rong Liu, Liu-Feng Zheng* and Jing Li*, Lipid profiles of Chinese soft-shell turtle eggs (Pelodiscus sinensis), Journal of Food Composition and Analysis, 2020, 94: 103627.

16. Liufeng Zheng, Yangtao Hu, Xingping He, Yu Zhao and Hengyi Xu, Isolation of swine‐derived Lactobacillus plantarum and its synergistic antimicrobial and health‐promoting properties with ZnO nanoparticles, Journal of Applied Microbiology, 2020, 128(6): 1764-1775.

17. Liufeng Zheng, Xinying Yu, Changhao Wei, Leyun Qiu, Chenwei Yu, Qian Xing, Yawei Fan and Zeyuan Deng, Production and characterization of a novel alkaline protease from a newly isolated Neurospora crassa through solid-state fermentation, LWT, 2020, 122: 108990.

18. Liuying Zhu, Juan Li, Changhao Wei, Ting Luo, Zeyuan Deng, Yawei Fan and Liufeng Zheng, A polysaccharide from Fagopyrum esculentum Moench bee pollen alleviates microbiota dysbiosis to improve intestinal barrier function in antibiotic-treated mice, Food & Function, 2020, 11(12): 10519-10533.

19. Jingfang Li, Yong Qin, Xiuliang Yu, Zengxing Xiong, Liufeng Zheng, Yong Sun, Jinrong Shen, Nansheng Guo, Lin Tao and Zeyuan Deng, In vitro simulated digestion and in vivo metabolism of chlorogenic acid dimer from Gynura procumbens (Lour.) Merr.: Enhanced antioxidant activity and different metabolites of blood and urine, Journal of Food Biochemistry, 2019, 43(6): e12654.

20. Liufeng Zheng, Li Chen, Jing Li, Li Liang, Yawei Fan, Leyun Qiu and Zeyuan Deng, Two kaempferol glycosides separated from camellia oleifera meal by high‐speed countercurrent chromatography and their possible application for antioxidation, Journal of Food Science, 2019, 84(10): 2805-2811.

21. Liufeng Zheng, Hongkui Wei, Huichao Yu, Qian Xing, Yi Zou, Yuanfei Zhou and Jian Peng, Fish skin gelatin hydrolysate production by ginger powder induces glutathione synthesis to prevent hydrogen peroxide induced intestinal oxidative stress via the Pept1-p62-Nrf2 cascade, Journal of agricultural and food chemistry, 2018, 66(44): 11601-11611.

22. Liufeng Zheng, Huichao Yu, Hongkui Wei, Qian Xing, Yi Zou, Yuanfei Zhou and Jian Peng, Antioxidative peptides of hydrolysate prepared from fish skin gelatin using ginger protease activate antioxidant response element-mediated gene transcription in IPEC-J2 cells, Journal of Functional Foods, 2018, 51: 104-112.

23. Liufeng Zheng, Hongkui Wei, Pingli He, Shengjun Zhao, Quanhang Xiang, Jiaman Pang and Jian Peng, Effects of supplementation of branched-chain amino acids to reduced-protein diet on skeletal muscle protein synthesis and degradation in the fed and fasted states in a piglet model, Nutrients, 2017, 9(1): 17.

24. Liufeng Zheng, Fangrui Zuo, Shengjun Zhao, Pingli He, Hongkui Wei, Quanhang Xiang, Jiaman Pang and Jian Peng, Dietary supplementation of branched-chain amino acids increases muscle net amino acid fluxes through elevating their substrate availability and intramuscular catabolism in young pigs, British Journal of Nutrition, 2017, 117(7): 911-922.

25. Liufeng Zheng, Hongkui Wei, Chuanshang Cheng, Quanhang Xiang, Jiaman Pang and Jian Peng, Supplementation of branched-chain amino acids to a reduced-protein diet improves growth performance in piglets: involvement of increased feed intake and direct muscle growth-promoting effect, British Journal of Nutrition, 2016, 115(12): 2236-2245.

26. Liufeng Zheng, Wei Zhang, Yuanfei Zhou, Fengna Li, Hongkui Wei and Jian Peng, Recent advances in understanding amino acid sensing mechanisms that regulate mTORC1, International journal of molecular sciences, 2016, 17(10): 1636.