Personal Information
Ph.D., Professor, Doctoral Supervisor.
Director, the Institute of Nutritional Sciences, Nanchang University
Principal Investigator, the State Key Laboratory of Food Science and Resources, Nanchang University
Vice President, the Traditional Chinese Medicine and Agricultural Industry Association of the World Federation of Traditional Chinese Medicine
Editor-in-Chief of Current Nutrition and Food Science
Associate Editor of Frontiers in Microbiology
Editor of Metabolism and Target Organ Damage
Editor of Foods
Editor of Discover Food
Email: ruanzheng@ncu.edu.cn
Homepage: http://www.foodchina.org/ruan/
I have published more than 140 papers, including 105 papers indexed by SCI and 36 papers (Chinese).
33 H-Index by web of science, 38 H-Index by scopus
https://webofscience.clarivate.cn/wos/author/record/IUM-7758-2023
https://www.scopus.com/authid/detail.uri?authorId=17344349500
https://orcid.org/0000-0001-9638-1466
https://scholar.google.com/citations?user=LpPfsEwAAAAJ&hl=en
https://www.researchgate.net/profile/Zheng-Ruan
Scientific Research Achievements
Preliminary revealed the pathways of in vitro fermentation biotransformation and in vivo metabolism of phenolic acids, a key class of food bioactive molecules.Our next step is to focus on polyphenols and terpenoids, the main active ingredients in food and pharmaceutical plants.
Developed nutritional and phyto-bioactive intervention strategies targeting gastrointestinal and enterohepatic metabolic dysfunction (chronic diseases), achieving effective intervention and mechanistic elucidation for various chronic conditions, including enteritis, fatty liver, and inflammatory anemia.
Scientific Research
1, Nutritional biochemistry and metabolism
This direction focuses on the molecular aspects of nutrition, particularly the metabolism of amino acids and phenolic acids. We aim to uncover new insights into their roles in health, disease prevention, and therapeutic strategies. Techniques in metabolomics will be employed to profile these nutrient metabolites and their impact on bodily functions.
2, Gut health: intestinal inflammation, gut microbiome and metabolites interactions
This area investigates the complex relationships between intestinal inflammation, the gut microbiome, and the metabolites that influence immunity or inflammatory bowel disease. Using metabolomic and genomic approaches, we will explore how dietary components and microbial interactions within the gut contribute to or mitigate inflammation and its related disorders. This research will provide a deeper understanding of the gut as a critical nexus in health and disease.
3, Mechanisms of fatty liver disease and nutritional interventions
Focusing on anti-inflammation and lipid metabolism of fatty liver disease, this direction aims to elucidate the disease's mechanisms with a strong emphasis on nutritional interventions. By integrating dietary strategies, immunomodulation and functional food development, we will investigate how specific nutrients and dietary patterns can prevent or reverse fatty liver disease.
4, Development of functional foods and personalized nutrition
This innovative direction seeks to design and test functional foods (prebiotics, probiotics, synbiotics, and postbiotics) that address specific health issues, especially intestinal inflammation, metabolic disorders, and fatty liver disease. Personalized nutrition, guided by genomics, metabolomics and algorithm, will tailor nutrition and dietary recommendations to populations with very similar biochemical, metabolic and inflammatory profiles.