Research Focus

Breeding of Elite Aquatic Varieties and Healthy Aquaculture

Major Honors & Professional Affiliation

2018-2022 Member, Teaching Advisory Board for Aquatic Science Programs in Higher Education, Ministry of Education

Member, 10th Freshwater Aquaculture Branch, Chinese Society of Fisheries

Standing Director, 1st Council, Jiangxi Society of Ecological Aquaculture

Director, 7th Council, Jiangxi Society of Fisheries

Head, Aquatic Science and Technology Mission, Jinggangshan City, Jiangxi Province

University-level Distinguished Talent

Director, Department of Aquatic Sciences, School of Life Sciences, Nanchang University

Education

1997/09 – 2001/07 BSc in Hydrobiology, Shanghai Fisheries University

2001/09 – 2004/07 MSc in Aquaculture, Shanghai Fisheries University

2006/09 – 2009/07 PhD in Zoology, East China Normal University

Professional Experience

2004/07 – Present Faculty Member (Assistant Professor-Lecturer-Associate Professor-Professor), School of Life Sciences, Nanchang University

2012/06 – 2016/05 Postdoctoral Fellow, School of Resources and Environmental Engineering, Nanchang University

2013/04 – 2014/03 Visiting Scholar, University of Florida, USA

Courses Taught

Undergraduate Courses

Aquatic Plant and Animal Culture

Culture of Special Economic Aquatic Animals

Nutrition and Feed Science for Aquatic Animals

Culture of Mollusks and Crustaceans

Postgraduate Courses

Introduction to Aquaculture Science

Research Methods in Aquatic Sciences

Principal Investigator (PI) Projects

1. National Key R&D Program (Blue Granary Science and Technology Innovation Special Project): Integration, Demonstration, and Promotion of Breeding, Cultivation, and Processing Technologies for Cold-Water Aquatic Animals in Jinggangshan

2. Jiangxi Modern Agricultural Industry Technology System: Expert of the Elite Variety Breeding Position in the Jiangxi Major Freshwater Fish Industry Technology System

3. Major Project of Jiangxi Provincial Department of Science and Technology: Study on the Ecological and Healthy Aquaculture Model of Eriocheir sinensis Based on Critical Point Control and Pollution Load Analysis

4. National Natural Science Foundation of China (Regional Program): Molecular Mechanism of the PXN-Integrin-eSOD Complex in Regulating the Immune Response of Eriocheir sinensis

5. National Natural Science Foundation of China (Regional Program): Mechanism of Action of the Cell Adhesion Molecule Peroxinectin in the Innate Immune Response of Eriocheir sinensis

6. National Natural Science Foundation of China (Regional Program): Immune Recognition Mechanism of Eriocheir sinensis Based on the Interaction Between LGBP and Integrin

7. Sixth Special Funding Project of the China Postdoctoral Science Foundation: Cloning of the Integrin Gene and Its Immune Regulatory Mechanism in Eriocheir sinensis

8. Excellent Funding Project for Postdoctoral Researchers in Jiangxi Province: Study on the Immune Regulatory Mechanism of β-1,3-Glucan and Lipopolysaccharide Binding Protein (LGBP) in Eriocheir sinensis

9. Jiangxi Provincial Natural Science Foundation (Youth Program): Screening and Functional Verification of Disease Resistance-Related Genes in Eriocheir sinensis

10. Project of Jiangxi Provincial Department of Education: Study on the Immune Recognition Mechanism of β-1,3-Glucan and Lipopolysaccharide Binding Protein (LGBP) in Eriocheir sinensis

Representative Publications

1. Wang Z, Li L, Han Y, Jian S, Hou J, Huang P, Fan H, Zhao D. Immune-related function and pro-phenol oxidase system regulation of pacifastin-type serine protease inhibitor in Eriocheir sinensis. Fish Shellfish Immunol. 2025 Aug;163:110364. doi: 10.1016/j.fsi.2025.110364. Epub 2025 Apr 28. PMID: 40306379.

2. Fan,H. ,Huang,P., Zhu,J., Li,J., Jian,S., Hou,J., Wang,Z., Li,L., Zhao,D. Effects of Artificial Compound Feed for Live  Fish Feed on Growth Performance, Nutrient Composition, Digestive Performance and Gut Microbiota of Giant Salamander (Andriasdavidianus). Fishes 2025,10,11.

3. Li L, Li X, Zeng L, Wang Z, Deng N, Huang P, Hou J, Jian S, Zhao D. Molecular mechanism of the NOS/NOX regulation of antibacterial activity in Eriocheir sinensis. Comp Biochem Physiol B Biochem Mol Biol. 2024 Apr-May;271:110945. doi: 10.1016/j.cbpb.2024.110945. Epub 2024 Jan 24. PMID: 38278206.

4. Mei F, Zhang C, Luo B, Zhang D, Hu S, Bao J, Lian Y, Zhao D. and Duan M. Effects of season and diel cycle on hydroacoustic estimates of density, Target Strength, and vertical distribution of fish in Yudong Reservoir, a plateau deep water reservoir in south west China. Front. 2023. Mar.Sci. 9:1119410.

5. Li LJ, Zhang CZ, Lin QC, Zhu MJ, Mei F, Jian SQ, Zhao DX*. Role of peroxinectin in the antibacterial immune response of the Chinese mitten crab, Eriocheir sinensis. Fish and Shellfish Immunology, 2022, 123: 496–505.

6. Zhao DX, Cheng C, Xiao M, Zhu MJ, Li LJ, Mei F, Zha YF, Jian SQ. Effects of stocking density on growth, antioxidant enzyme activity, and related gene expression in juvenile Siberian sturgeon hybrids. Journal of Fisheries of China (Online First), 2022, DOI: 10.11964/jfc.202105 12834.

7. Zhao DX, Mao ZF, Lin QC, Qin CJ, Hong YJ. Effect of supplementary manganese on growth performance, tissue manganese content, antioxidant activities, and cytosolic manganese superoxide dismutase gene mRNA expression in juvenile Chinese mitten crabs (Eriocheir sinensis). Aquaculture International, 2017, 25(2): 893–903.

8. Zhao DX, Qin CJ, Fan XH, et al. Inhibitory effects of quercetin on angiogenesis in larval zebrafish and human umbilical vein endothelial cells. European Journal of Pharmacology, 2014, 723: 360–367.

9. Zhao DX, Chen LQ, Qin JG, Qin CJ, Zhang H, Wu P, Li EC. Molecular characterization of a cytosolic manganese superoxide dismutase from the Chinese mitten crab Eriocheir sinensis. Genetics and Molecular Research, 2014, 13(13): 9429–9442.

10. Zhao DX, Chen LQ, Qin CJ, et al. A delta-class glutathione transferase from the Chinese mitten crab Eriocheir sinensis: cDNA cloning, characterization and mRNA expression. Fish and Shellfish Immunology, 2010, 29: 698–703.

11. Zhao DX, Chen LQ, Qin CJ, et al. Molecular cloning and characterization of the lipopolysaccharide and β-1,3-glucan binding protein in Chinese mitten crab (Eriocheir sinensis). Comparative Biochemistry and Physiology - Part B, 2009, 154(1): 17–24.

12. Zhao DX, Song SH, Wang Q, et al. Discovery of immune-related genes in Chinese mitten crab (Eriocheir sinensis) by expressed sequence tag analysis of haemocytes. Aquaculture, 2009, 287(3–4): 297–303.